Spectrum of Antiepileptic Drug Interactions: Perspective on Valproate

Please Note: This CME activity has expired. You may continue to view the material for educational purposes, but this activity is no longer eligible for CME credit.

Course Objectives:
This CME-certified monograph is intended for physicians who treat epilepsy.
Upon completing this activity, you should be able to:

1. Describe and contrast enzyme induction and enzyme inhibition.
2. Identify current and possible drug interactions with valproate.
3. Understand how to manage potential drug interactions with valproate.

Accreditation:
Millennium CME Institute, Inc. proudly acknowledges its academic partnership with the UMDNJ - Center for Continuing and Outreach Education in the development of this activity and in the review of the educational content. Millennium CME Institute, Inc. has assumed the responsibility for long-term retention of individual credit records.

This activity was reviewed for relevance, accuracy of content, balance of presentation, and time required for participation by David A. Marks, MD; Peter Boardman, MD; Verma Navin, MD; and Olga Bogdanova, MD.

Release Date: September, 2005
Expiration Date: September 30, 2006

Physicians
Millennium CME Institute, Inc. is accredited by the ACCME to provide continuing medical education for physicians.

Millennium CME Institute, Inc. designates this educational activity for a maximum of 1.0 Category 1 Credits toward the AMA Physician’s Recognition Award. Each physician should claim only those credits that he/she actually spent in the activity.

© 2005 Millennium CME Institute, Inc. and UMDNJ - Center for Continuing and Outreach Education. All rights reserved including translation into other languages. No part of this activity may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopying, recording, or any information storage and retrieval systems, without permission in writing from Millennium CME Institute, Inc. and UMDNJ - Center for Continuing and Outreach Education.

Faculty Disclosure:
The opinions expressed in this activity are those of the faculty. It should not be inferred or assumed that they are expressing the views of Abbott Laboratories, any other manufacturer of pharmaceuticals, or the University of Medicine & Denstistry of New Jersey (UMDNJ), or Millennium CME Institute, Inc. The drug selection and dosage information presented in this activity are believed to be accurate. However, participants are urged to consult the full prescribing information on any agent(s) presented in this activity for recommended dosage, indications, contra-indications, warning, precautions, and adverse effects before prescribing any medication. This is particularly important when a drug is new or infrequently prescribed.

Disclosure of Significant Relationships with Relevant Commercial Companies/Organizations

Millennium CME Institute, Inc. endorses the Accreditation Council for Continuing Medical Education (ACCME) Standards for Commercial Support. All faculty are required to disclose any commercial relationships or personal benefit with companies whose products are discussed in educational presentations and with companies who have provided the commercial support for this activity. Disclosure of a relationship is not intended to suggest or condone bias in any presentation, but is made to provide participants with information that might be of potential importance to their evaluation of a presentation.

The faculty listed below have declared that they have no relationships to disclose:

David A.Marks,MD
Peter Boardman,MD
Verma Navin,MD
Olga Bogdanova,MD

The faculty listed below have declared the following arrangements and/or affiliations:

Carol Collins, MD: Nothing to disclose.
Rene Levy, PhD: Nothing to disclose.
Peter Boardman, MD: Nothing to disclose.
Verma Navin, MD: Nothing to disclose.
Olga Bogdanova, MD: Nothing to disclose.

Signed disclosure forms are on file at Millennium CME Institute, Inc.

Directions:
The learner should read the learning objectives and review the activity in its entirety. After reviewing the material, the learner should complete the Activity Self-assessment Test consisting of a series of multiple-choice questions.

Upon successfully completing this activity as designed and achieving a passing score of 70% or more on the Self-assessement Test, participants will receive a continuing education credit letter awarding the appropriate credit.

Estimated time to complete this activity as designed is 1.0 hours.

CME Testing Options