Differentiating Niacin Formulations Used to Treat Lipid Disorders: Analysis of Efficacy, Safety and Tolerability Profiles

Please Note: This CME activity has expired. You may continue to view the material for educational purposes, but this activity is no longer eligible for CME credit.

Course Objectives:
This CME-certified monograph is intended for US-based Physicians and Pharmacists.
Upon completing this activity, you should be able to:

1. Recognize the role of low HDL-cholesterol as a cardiovascular disease risk factor and discuss the effective management of cardiovascular risk using statin/niacin combination therapy.
2. Review the efficacy of niacin on lipid profiles and in further reducing cardiovascular risk compared with statins alone, or statins in combination with fibrates or ezetimibe.
3. Discuss the long-term safety of extended-release niacin and its side effects, ie, cutaneous flushing and how best to circumvent using ASA predosing.

Accreditation:
This activitywas reviewed for relevance, accuracy of content, balance of presentation, and time required for participation by Abigail Zavod, MD, MPH, Paula Brathwaite, MD, and Alexandra Mangili, MD.

Release Date: March 2008
Expiration Date: March 31, 2009

Millennium CME Institute, Inc., is accredited by the ACCME to provide continuing medical education for physicians.
Millennium CME Institute, Inc., designates this CME-certified monograph for a maximum of 1.0 AMA PRA Category 1 Credit™. Physicians should only claim credit commensurate with the extent of their participation in the activity.

This activity is approved for 1.0 credit hour (0.1 CEU).
TG Medical Education is accredited by the Accreditation Council for Pharmacy Education (ACPE) as a provider of continuing pharmacy education. The program number is 454-999-08-005-H01-P and release date is 3/27/2008.

Faculty Disclosure:
Millennium CME Institute, Inc., endorses the Accreditation Council for Continuing Medical Education (ACCME) Standards for Commercial Support. All faculty are required to disclose any commercial relationships or personal benefit with companies whose products are discussed in educational presentations and with companies who have provided the commercial support for this activity. Disclosure of a relationship is not intended to suggest or condone bias in any presentation, but is made to provide participants with information that might be of potential importance to their evaluation of a presentation. The faculty listed below have declared that they have no relationships to disclose:
Paula Brathwaite, MD
Alexandra Mangili, MD
Peter B. Lindgren, PhD
Tim I. Robinson
Frank A.Gesek, PhD, RPh
Abigail Zavod,MD,MPH

The faculty listed below have declared the following arrangements and/or affiliations:
Richard H.Karas,MD, PhD:Speakers Bureau — Abbott

Off-label Usage Disclosure
This CME activity contains information on commercial products/devices that are unlabeled for use or investigational uses of products not yet approved.

Directions:
The learner should read the learning objectives and review the activity in its entirety. After reviewing the material, the learner should complete the Activity Self-assessment Test consisting of a series of multiple-choice questions.
Upon successfully completing this activity as designed and achieving a passing score of 70% or higher on the Activity Self-assessment Test, participants will receive a continuing education credit letter awarding the appropriate credit and the Activity Self-assessment Test answers four to six weeks after the receipt of the registration and evaluation materials.
Estimated time to complete this CME-certified monograph as designed is 1.0 hours.

CME Testing Options